SCHEMBL2855872

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13178572	0.83	SLC7A5 (0.50)	HSP90AB1CYP4F2CYP4A11ALDH1A1GAA
	SCHEMBL9732769	0.82	ALDH1A1 (0.56)	HSP90AB1CYP4F2CYP4A11ALDH1A1GAA
	SCHEMBL348963	0.81	HSP90AB1 (0.62)	HSP90AB1CYP4F2CYP4A11ALDH1A1GAA
	SCHEMBL14626264	0.79	HSP90AB1 (0.51)	HSP90AB1CYP4F2CYP4A11ALDH1A1GAA
	SCHEMBL2857252	0.78	HSP90AB1 (0.50)	HSP90AB1CYP4F2CYP4A11ALDH1A1GAA
	SCHEMBL21891794	0.78	HSP90AB1 (0.75)	HSP90AB1CYP4F2CYP4A11ALDH1A1GAA
	SCHEMBL14558932	0.77	HSP90AB1 (0.53)	HSP90AB1CYP4F2CYP4A11ALDH1A1GAA
	SCHEMBL490786	0.77	MEN1 (0.59)	HSP90AB1ALDH1A1NPC1RAB9AHPGD
	SCHEMBL27088422	0.77	PLA2G2A (0.58)	HSP90AB1
	SCHEMBL31225523	0.76	MAOB (0.42)	ALDH1A1GAAMAPTHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.