Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475360 | 0.85 | L3MBTL1 (0.56) | TDP1L3MBTL1KDM4EPOLBALDH1A1 | |
| SCHEMBL5481728 | 0.78 | MAPT (0.48) | KDM4EPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28331716 | 0.77 | TDP1 (0.38) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL28150861 | 0.75 | TSHR (0.43) | TDP1L3MBTL1KDM4EPOLBALDH1A1 | |
| SCHEMBL1121873 | 0.75 | GPR35 (0.50) | TDP1L3MBTL1KDM4EPOLBALDH1A1 | |
| SCHEMBL2773204 | 0.74 | TDP1 (0.54) | TDP1L3MBTL1KDM4EPOLBALDH1A1 | |
| SCHEMBL161321 | 0.74 | SIRT3 (0.46) | TDP1POLBNTRK1PIM1MKNK1 | |
| SCHEMBL31606794 | 0.74 | SIRT3 (0.46) | TDP1POLBNTRK1PIM1MKNK1 | |
| SCHEMBL11620693 | 0.73 | POLB (0.41) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL11723471 | 0.73 | TDP1 (0.41) | TDP1L3MBTL1KDM4EPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112710767-A | Tandem mass spectrometry kit for measuring NNMT catalytic substrate and NNMT catalytic product | 浙江大学 | 2021-04-27 | — | — | CN | claimed |