Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475360 | 0.80 | L3MBTL1 (0.56) | MAPTALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL28560223 | 0.78 | TDP1 (0.42) | MAPTNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL306569 | 0.78 | CA12 (0.50) | MAPTNPC1RAB9AALDH1A1PDE4D | |
| SCHEMBL1243723 | 0.77 | AR (0.44) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| SCHEMBL25529027 | 0.76 | CA12 (0.62) | MAPTNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL5764011 | 0.76 | TDP1 (0.64) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| SCHEMBL27249061 | 0.75 | ALDH1A1 (0.51) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| SCHEMBL8840548 | 0.75 | PDE4B (0.48) | MAPTNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL14351781 | 0.75 | HTT (0.50) | MAPTNPC1RAB9AALDH1A1PDE4D | |
| SCHEMBL31214404 | 0.75 | HTT (0.50) | MAPTNPC1RAB9AALDH1A1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |