Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27986023 | 0.87 | ESR2 (0.46) | ALDH1A1MAPK1NQO2PPARGPRNP | |
| SCHEMBL20873646 | 0.82 | MAPT (0.43) | ALDH1A1TDP1PPARGPPARALMNA | |
| SCHEMBL1133458 | 0.80 | PSMB5 (0.46) | ALDH1A1PPARGPPARALMNAMAPT | |
| SCHEMBL21888213 | 0.80 | L3MBTL1 (0.53) | ALDH1A1MAPK1NQO2TDP1LMNA | |
| SCHEMBL20257712 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPK1NQO2LMNAESR2 | |
| Hydrogen Sulfide SCHEMBL21381346 | 0.78 | PSMB5 (0.44) | ALDH1A1PPARGPPARALMNAMAPT | |
| SCHEMBL13176919 | 0.78 | CYP1A2 (0.46) | ALDH1A1TDP1PPARGPPARALMNA | |
| Lithium SCHEMBL30636805 | 0.78 | PSMB5 (0.44) | ALDH1A1PPARGPPARALMNAMAPT | |
| SCHEMBL1696315 | 0.77 | ALDH1A1 (0.33) | ALDH1A1NQO2TDP1 | |
| SCHEMBL1513560 | 0.76 | ESR2 (0.57) | ALDH1A1PPARGPPARALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685593-B | Compound and organic electroluminescent device comprising the same | 出光兴产株式会社 | 2025-05-13 | — | — | CN | disclosed |
| US-20240244972-A1 | COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND | IDEMITSU KOSAN CO., LTC. (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240244972-A1 | COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND | IDEMITSU KOSAN CO., LTC. (JP) | 2024-07-18 | — | — | US | disclosed |
| CN-116685593-A | Compound and organic electroluminescent device comprising the same | 出光兴产株式会社 | 2023-09-01 | — | — | CN | disclosed |
| CN-112601753-A | Fluorine substituted polycyclic aromatic compound | 学校法人关西学院 | 2021-04-02 | — | — | CN | disclosed |
| CN-110483670-A | The method of metallocene complex and production olefin polymer | JAPAN POLYPROPYLENE CORP | 2019-11-22 | — | — | CN | disclosed |
| CN-106132975-B | Metallocene complex and process for producing olefin polymer | 日本聚丙烯株式会社 | 2019-11-08 | — | — | CN | disclosed |
| EP-3121187-B1 | METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER | JAPAN POLYPROPYLENE CORP (JP) | 2018-10-10 | — | — | EP | disclosed |
| US-9963522-B2 | Metallocene complex and method for producing olefin polymer | JAPAN POLYPROPYLENE CORPORATION (JP) | 2018-05-08 | — | — | US | disclosed |
| US-20170081431-A1 | METALLOCENE COMPLEX AND METHOD FOR PRODUCING OLEFIN POLYMER | JAPAN POLYPROPYLENE CORPORATION (JP) | 2017-03-23 | — | — | US | disclosed |
| EP-3121187-A1 | METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER | Japan Polypropylene Corporation (JP) | 2017-01-25 | — | — | EP | disclosed |
| CN-106132975-A | metallocene complex and process for producing olefin polymer | 日本聚丙烯株式会社 | 2016-11-16 | — | — | CN | disclosed |
| US-7868030-B2 | FBPase inhibitors for diabetes | HOFFMANN-LA ROCHE INC. (US) | 2011-01-11 | — | — | US | disclosed |
| EP-2032548-A1 | THIAZOLE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007137962-A1 | THIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-12-06 | — | — | WO | disclosed |
| US-20070281979-A1 | Fructose-1,6-bisphosphatase (FBPase) inhibitors, such as N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]3(difluoromethoxy)benzenesulfonamide, used as antidiabetic agents | HOFFMANN-LA ROCHE INC. | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281979-A1 | Fructose-1,6-bisphosphatase (FBPase) inhibitors, such as N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]3(difluoromethoxy)benzenesulfonamide, used as antidiabetic agents | FBP1, PFKFB1, PFKFB3 | ALDH1A1 565/4885MAPK1 1042/4885NQO2 228/4885 |
| US-20170081431-A1 | METALLOCENE COMPLEX AND METHOD FOR PRODUCING OLEFIN POLYMER | PPOX, ALOX12, PORCN | ALDH1A1 1301/4885MAPK1 2819/4885NQO2 4497/4885 |
| US-20240244972-A1 | COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND | DDT, ODC1, AOC2 | ALDH1A1 31/4885MAPK1 1838/4885NQO2 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.