Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 7/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28550266 | 0.91 | ROCK1 (0.35) | CHEK2ROCK1FDPSPRMT3IRAK4 | |
| SCHEMBL28550771 | 0.91 | IRAK4 (0.35) | ROCK1FDPSPRMT3IRAK4 | |
| SCHEMBL18322869 | 0.84 | FDPS (0.35) | CHEK2ROCK1FDPSIRAK4ABL1 | |
| SCHEMBL18319103 | 0.83 | CHEK2 (0.43) | CHEK2ROCK1FDPSPRMT3MAP4K4 | |
| SCHEMBL18318344 | 0.79 | PIK3CD (0.45) | PRMT3 | |
| SCHEMBL28566516 | 0.79 | PIK3C3 (0.42) | CHEK2FDPSKDM4ELMNAMAPT | |
| SCHEMBL18318354 | 0.79 | FDPS (0.42) | CHEK2ROCK1FDPSPRMT3WNT1 | |
| SCHEMBL18322849 | 0.78 | HRH3 (0.48) | ROCK1FDPSKDM4E | |
| SCHEMBL18318448 | 0.77 | JUN (0.44) | FDPSPRMT3 | |
| SCHEMBL18318252 | 0.77 | NAMPT (0.41) | CHEK2ROCK1FDPSPRMT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107847765-B | 1, 4-substituted piperidine derivatives | 89生物有限公司 | 2021-05-04 | — | — | CN | disclosed |