Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HCK | P08631 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18322908 | 0.81 | PIK3C3 (0.49) | PIK3C3HRH3CHEK2MAP4K4FDPS | |
| SCHEMBL28566752 | 0.80 | KDM4E (0.33) | HRH3CHEK2KDM4ELMNAMAPT | |
| SCHEMBL28560642 | 0.79 | CHEK2 (0.36) | CHEK2KDM4ELMNAMAPTMAP4K4 | |
| SCHEMBL18319428 | 0.77 | PIK3C3 (0.47) | PIK3C3HRH3EPHX2KMT2A | |
| Hydrochloric Acid SCHEMBL18319008 | 0.76 | PIK3C3 (0.46) | PIK3C3HRH3EPHX2KMT2A | |
| Hydrochloric Acid SCHEMBL18322940 | 0.76 | PIK3C3 (0.49) | PIK3C3HRH3CHEK2MAP4K4FDPS | |
| SCHEMBL28571679 | 0.76 | HCRTR2 (0.33) | HRH3CHEK2PIK3CDKMT2A | |
| SCHEMBL28560945 | 0.74 | KMT2A (0.32) | HRH3CHEK2NEK2EPHX2KMT2A | |
| SCHEMBL28912555 | 0.74 | GPR119 (0.51) | PIK3C3HRH3CHEK2 | |
| SCHEMBL28912535 | 0.73 | KMT2A (0.32) | CHEK2NEK2PIK3CDEPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107847765-B | 1, 4-substituted piperidine derivatives | 89生物有限公司 | 2021-05-04 | — | — | CN | disclosed |