Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
| ▸ | HEXB | P07686 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR7 | P34969 | 5/20 | 0.34 |
| ▸ | HTR6 | P50406 | 5/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28563228 | 0.90 | HTR1A (0.36) | ADORA2AADORA3ADORA1ADORA2BPOLB | |
| SCHEMBL28566839 | 0.87 | HTR1A (0.38) | ADORA2AADORA3ADORA1ADORA2BPOLB | |
| SCHEMBL28563239 | 0.86 | TLR8 (0.40) | DHFRHTR2AHTR7HTR6HTR1A | |
| SCHEMBL28569887 | 0.85 | DHFR (0.40) | DHFRHTR2AHTR7HTR6HTR1A | |
| SCHEMBL28569800 | 0.80 | CYP17A1 (0.36) | ADORA2AADORA3ADORA1ADORA2BPOLB | |
| SCHEMBL28559984 | 0.77 | HRH4 (0.30) | — | |
| SCHEMBL28559976 | 0.72 | L3MBTL1 (0.36) | ADORA2AADORA3ADORA1ADORA2BPOLB | |
| SCHEMBL28572014 | 0.71 | L3MBTL1 (0.35) | ADORA2AADORA3ADORA1ADORA2BPOLB | |
| SCHEMBL28559977 | 0.70 | CYP17A1 (0.39) | ADORA2AADORA3ADORA1ADORA2BPOLB | |
| SCHEMBL28563811 | 0.67 | TSHR (0.44) | POLBDHFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724596-A | Curable composition and cured product | 盛势达技研株式会社 | 2021-04-30 | — | — | CN | disclosed |