Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834893 | 0.81 | GPR119 (0.38) | SSTR4GPR119POLBMETAP1ALDH1A1 | |
| SCHEMBL31009098 | 0.78 | GPR119 (0.36) | SSTR4GPR119POLBMETAP1ALDH1A1 | |
| SCHEMBL28547830 | 0.73 | CYP3A4 (0.40) | SSTR4ALDH1A1LMNAKMT2ACYP2C19 | |
| SCHEMBL19512762 | 0.73 | L3MBTL1 (0.42) | PAX8LMNAKMT2AF2CYP2C19 | |
| SCHEMBL2244045 | 0.72 | KMT2A (0.35) | ALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL20794554 | 0.71 | HTR2C (0.43) | SSTR4GPR119POLBALDH1A1PAX8 | |
| SCHEMBL29100779 | 0.71 | POLB (0.43) | GPR119POLBALDH1A1LMNAKMT2A | |
| SCHEMBL31613428 | 0.71 | SSTR4 (0.41) | SSTR4 | |
| SCHEMBL30676280 | 0.70 | POLB (0.46) | GPR119POLBALDH1A1LMNAKMT2A | |
| SCHEMBL15390791 | 0.70 | POLB (0.46) | GPR119POLBALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-A | PRMT5 inhibitor | 默沙东公司 | 2021-05-14 | — | — | CN | disclosed |