Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28563891 | 0.80 | HTT (0.39) | ALDH1A1RAB9APOLBNPC1MAPT | |
| SCHEMBL28564315 | 0.77 | TERT (0.49) | TERTALDH1A1MAPTSMN1; SMN2CHRNB4 | |
| SCHEMBL7230472 | 0.76 | SIRT2 (0.47) | ALDH1A1SIRT2RAB9APOLBNPC1 | |
| SCHEMBL31252799 | 0.76 | SIRT2 (0.47) | ALDH1A1SIRT2RAB9APOLBNPC1 | |
| SCHEMBL30778626 | 0.74 | TERT (0.44) | TERTALDH1A1SIRT2POLBSMN1; SMN2 | |
| SCHEMBL18227140 | 0.71 | TERT (0.48) | TERTALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL7237974 | 0.71 | SIRT2 (0.44) | ALDH1A1SIRT2RAB9APOLBNPC1 | |
| SCHEMBL7511291 | 0.71 | PNMT (0.41) | — | |
| SCHEMBL28566911 | 0.69 | MAPT (0.46) | TERTALDH1A1POLBMAPTCA12 | |
| SCHEMBL7238139 | 0.68 | ALDH1A1 (0.46) | ALDH1A1SIRT2RAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349233-B | 3, 4-diphenyl-4H-1, 2, 4-triazole derivative and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-06-01 | — | — | CN | disclosed |