Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622711 | 0.82 | ALDH1A1 (0.53) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL28400513 | 0.82 | ALDH1A1 (0.53) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL30622706 | 0.81 | MEN1 (0.33) | MAPTSLC9A1MEN1KMT2APDPK1 | |
| SCHEMBL28398556 | 0.81 | MEN1 (0.33) | MAPTSLC9A1MEN1KMT2APDPK1 | |
| SCHEMBL29099875 | 0.79 | MEN1 (0.34) | MAPTSLC9A1MEN1KMT2APDPK1 | |
| SCHEMBL30622702 | 0.79 | MEN1 (0.34) | MAPTSLC9A1MEN1KMT2APDPK1 | |
| SCHEMBL28782049 | 0.77 | NPC1 (0.34) | MAPTDYRK1AALDH1A1NPSR1NPC1 | |
| SCHEMBL10814903 | 0.76 | ALDH1A1 (0.44) | MAPTL3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL6632291 | 0.74 | CYP1A2 (0.54) | MAPTMEN1KMT2ADYRK1AALDH1A1 | |
| SCHEMBL28902824 | 0.72 | CLK1 (0.31) | DYRK1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-115557974-A | KRAS G12D inhibitor and application thereof | 上海迪诺医药科技有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-112805281-B | KRAS G12C inhibitors | 伊莱利利公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-112805281-A | KRAS G12C inhibitors | 伊莱利利公司 | 2021-05-14 | — | — | CN | disclosed |