Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28398556 | 1.00 | MEN1 (0.33) | MEN1KMT2APDPK1SMN1; SMN2MAPT | |
| SCHEMBL28564366 | 0.81 | MAPT (0.39) | MEN1KMT2APDPK1SMN1; SMN2MAPT | |
| SCHEMBL30622711 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL28400513 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL29099875 | 0.76 | MEN1 (0.34) | MEN1KMT2APDPK1SMN1; SMN2MAPT | |
| SCHEMBL30622702 | 0.76 | MEN1 (0.34) | MEN1KMT2APDPK1SMN1; SMN2MAPT | |
| SCHEMBL6632291 | 0.71 | CYP1A2 (0.54) | MEN1KMT2ASMN1; SMN2MAPTDYRK1A | |
| SCHEMBL28782049 | 0.70 | NPC1 (0.34) | MAPTDYRK1ANPC1RAB9AALDH1A1 | |
| SCHEMBL21821684 | 0.70 | MAPT (0.50) | MEN1KMT2AMAPTDYRK1ANPC1 | |
| SCHEMBL28902824 | 0.69 | CLK1 (0.31) | SMN1; SMN2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969904-A | Compounds useful as autophagy modulators, methods of preparation and uses thereof | 微境生物医药科技(上海)有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-111148740-B | Compounds useful as autophagy modulators, methods of preparation and uses thereof | 微境生物医药科技(上海)有限公司 | 2023-08-25 | — | — | CN | disclosed |