Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 15/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858076 | 0.92 | MAPT (0.56) | CCR1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2861197 | 0.90 | CCR1 (0.51) | CCR1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2856556 | 0.90 | CCR1 (0.54) | CCR1 | |
| SCHEMBL2853364 | 0.90 | CCR1 (0.52) | CCR1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2853351 | 0.88 | CCR1 (0.62) | CCR1NPSR1 | |
| SCHEMBL2860247 | 0.88 | CCR1 (0.59) | CCR1MAPT | |
| SCHEMBL2849956 | 0.87 | CCR1 (0.62) | CCR1MAPTNPSR1ATG4BMEN1 | |
| SCHEMBL2856514 | 0.87 | CCR1 (0.49) | CCR1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2856212 | 0.86 | CCR1 (0.47) | CCR1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2854330 | 0.86 | CCR1 (0.52) | CCR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |