Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CCR1 | P32246 | 9/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856460 | 0.92 | CCR1 (0.65) | MAPTNPC1RAB9ANPSR1CCR1 | |
| SCHEMBL2857994 | 0.89 | MTOR (0.46) | MAPTNPC1RAB9ANPSR1CCR1 | |
| SCHEMBL2861197 | 0.89 | CCR1 (0.51) | MAPTNPC1RAB9ANPSR1CCR1 | |
| SCHEMBL2863210 | 0.88 | CCR1 (0.50) | MAPTNPC1RAB9ANPSR1CCR1 | |
| SCHEMBL2854244 | 0.87 | ACHE (0.52) | MAPTNPC1RAB9ANPSR1CCR1 | |
| SCHEMBL2853270 | 0.87 | CCR1 (0.51) | MAPTNPC1RAB9ANPSR1CCR1 | |
| SCHEMBL2856212 | 0.86 | CCR1 (0.47) | MAPTNPC1RAB9ANPSR1CCR1 | |
| SCHEMBL2857073 | 0.86 | CCR1 (0.48) | MAPTCCR1TACR1 | |
| SCHEMBL2853364 | 0.85 | CCR1 (0.52) | MAPTNPC1RAB9ANPSR1CCR1 | |
| SCHEMBL2852545 | 0.85 | NPBWR1 (0.42) | NPSR1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |