Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861197 | 0.92 | CCR1 (0.51) | CCR1NPC1MAPTRAB9ANPSR1 | |
| SCHEMBL2856304 | 0.90 | KEAP1 (0.53) | CCR1KEAP1NFE2L2MAPTEPHX1 | |
| SCHEMBL2856460 | 0.90 | CCR1 (0.65) | CCR1NPC1MAPTRAB9ANPSR1 | |
| SCHEMBL2854462 | 0.89 | KEAP1 (0.48) | CCR1KEAP1NFE2L2MAPTEPHX1 | |
| SCHEMBL2856294 | 0.88 | CCR1 (0.49) | CCR1KEAP1NFE2L2EPHX1KDM4E | |
| SCHEMBL2859089 | 0.86 | ATG4B (0.43) | CCR1KEAP1NFE2L2ATG4BEPHX1 | |
| SCHEMBL2860700 | 0.86 | KEAP1 (0.46) | CCR1KEAP1NFE2L2EPHX1KDM4E | |
| SCHEMBL2856514 | 0.85 | CCR1 (0.49) | CCR1NPC1MAPTRAB9ANPSR1 | |
| SCHEMBL2858076 | 0.85 | MAPT (0.56) | CCR1NPC1MAPTRAB9ANPSR1 | |
| SCHEMBL2850321 | 0.85 | SMN1; SMN2 (0.47) | CCR1NPC1MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |