Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL1304649 | 1.00 | — | — | |
| Silver SCHEMBL1177402 | 0.93 | — | — | |
| Zinc Ion SCHEMBL491189 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15TP53ALDH1A1 | |
| SCHEMBL17092605 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15TP53ALDH1A1 | |
| SCHEMBL1404436 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15TP53ALDH1A1 | |
| SCHEMBL25252386 | 0.93 | — | — | |
| SCHEMBL2293214 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15TP53ALDH1A1 | |
| SCHEMBL17092588 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15TP53ALDH1A1 | |
| SCHEMBL1138504 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15TP53ALDH1A1 | |
| SCHEMBL587040 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739332-A | Bioparticle, redox, methods and compositions | 奥尔吉尼西丝公司 | 2021-04-30 | — | — | CN | claimed |
| CN-115884751-A | Cosmetic composition providing unique sensory feel | 莱雅公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115803000-A | Cosmetic composition with stabilized retinol | 莱雅公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-114207100-A | Toilet block with improved gloss | 汉高股份有限及两合公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-112739332-A | Bioparticle, redox, methods and compositions | 奥尔吉尼西丝公司 | 2021-04-30 | — | — | CN | disclosed |