Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28946651 | 0.91 | CA12 (0.48) | CYP19A1MEN1MAPTKMT2ACRHBP | |
| SCHEMBL28705413 | 0.85 | CA2 (0.50) | CYP19A1MEN1MAPTKMT2ACRHBP | |
| SCHEMBL7526079 | 0.82 | CA2 (0.53) | CA1CA2CA12CA9CA7 | |
| SCHEMBL29988503 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2ACA1CA2CA12 | |
| SCHEMBL6199119 | 0.80 | NPSR1 (0.55) | CYP19A1MEN1MAPTKMT2ACRHBP | |
| SCHEMBL28956715 | 0.79 | NPSR1 (0.54) | CYP19A1MEN1MAPTKMT2ACRHBP | |
| SCHEMBL29799257 | 0.77 | CA2 (0.49) | CYP19A1MEN1KMT2ACA1CA2 | |
| SCHEMBL14880488 | 0.77 | KCNJ1 (0.63) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL7015694 | 0.77 | MTNR1A (0.52) | CA1CA2ALDH1A1HTTMAPK1 | |
| SCHEMBL29799247 | 0.77 | MTNR1A (0.52) | CA1CA2ALDH1A1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071533-B | Halogenated allylamine indole and azaindole derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2021-05-25 | — | — | CN | disclosed |