Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560877 | 0.85 | ACACA (0.44) | ALDH1A1KMT2AATMMEN1L3MBTL1 | |
| SCHEMBL28550126 | 0.85 | MAPK1 (0.50) | ALDH1A1KMT2AMEN1L3MBTL1RXFP1 | |
| SCHEMBL28550499 | 0.85 | PRNP (0.41) | PRNPPOLBALDH1A1RXFP1MAPT | |
| SCHEMBL28565686 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL28563728 | 0.82 | AURKA (0.47) | ALDH1A1KMT2AMEN1RXFP1MAPT | |
| SCHEMBL28550497 | 0.79 | GRM2 (0.42) | ALDH1A1KMT2AMEN1L3MBTL1GRM2 | |
| SCHEMBL28559495 | 0.79 | LTB4R (0.46) | KMT2AMEN1RXFP1PTGDR2TUBB4A | |
| SCHEMBL28554782 | 0.79 | GRM2 (0.39) | PRNPPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL28912506 | 0.77 | KDM4E (0.53) | POLBALDH1A1KMT2AMEN1RXFP1 | |
| SCHEMBL28313335 | 0.74 | HDAC1 (0.45) | KMT2AMEN1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106366035-B | Synthesis method of quinoline derivative | 南阳师范学院 | 2021-05-07 | — | — | CN | disclosed |