Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655983 | 0.89 | RAB9A (0.70) | RAB9ANPC1L3MBTL1GAAMEN1 | |
| SCHEMBL8655985 | 0.89 | RAB9A (0.70) | RAB9ANPC1L3MBTL1GAAMEN1 | |
| SCHEMBL29683217 | 0.89 | RAB9A (0.70) | RAB9ANPC1L3MBTL1GAAMEN1 | |
| Alcohol SCHEMBL28128761 | 0.83 | MAPT (0.75) | RAB9ANPC1L3MBTL1GAAMEN1 | |
| Alcohol SCHEMBL28565749 | 0.83 | MAPT (0.70) | RAB9ANPC1L3MBTL1GAAMEN1 | |
| SCHEMBL11318232 | 0.79 | MAPT (0.73) | RAB9ANPC1L3MBTL1GAAMEN1 | |
| SCHEMBL29001132 | 0.77 | NPC1 (0.76) | RAB9ANPC1L3MBTL1GAAMEN1 | |
| SCHEMBL29569176 | 0.77 | NPC1 (0.76) | RAB9ANPC1L3MBTL1GAAMEN1 | |
| SCHEMBL590787 | 0.77 | NPC1 (0.76) | RAB9ANPC1L3MBTL1GAAMEN1 | |
| SCHEMBL434865 | 0.77 | NPC1 (0.76) | RAB9ANPC1L3MBTL1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759777-B | Anti-ultraviolet self-repairing polymer and preparation method and application thereof | 山东师范大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-112759777-A | Anti-ultraviolet self-repairing polymer and preparation method and application thereof | 山东师范大学 | 2021-05-07 | — | — | CN | disclosed |