Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28372646 | 0.80 | EPHX1 (0.68) | EPHX1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL6964245 | 0.78 | ADRB1 (0.65) | FAAHKMT2AADRB1CYP1A2CYP2C9 | |
| SCHEMBL28562874 | 0.78 | KMT2A (0.66) | EPHX1HSD17B10FAAHRAB9AKMT2A | |
| SCHEMBL7083827 | 0.77 | ADRB1 (0.62) | ADRB1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4598628 | 0.77 | EPHX1 (0.68) | EPHX1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL4599565 | 0.77 | EPHX1 (0.68) | EPHX1HSD17B10FAAHRAB9AKMT2A | |
| SCHEMBL4599459 | 0.77 | EPHX1 (0.68) | EPHX1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL4197062 | 0.76 | EPHX1 (1.00) | EPHX1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL5101418 | 0.76 | KMT2A (0.82) | EPHX1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL15546841 | 0.75 | KMO (0.57) | EPHX1HSD17B10FAAHKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112752755-A | Heterocyclyl compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2021-05-04 | — | — | CN | disclosed |