Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 10/20 | 0.43 |
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21749380 | 0.87 | NPBWR1 (0.47) | NPBWR1THRATHRBMCHR1CRHR1 | |
| SCHEMBL28561074 | 0.83 | NPBWR1 (0.47) | NPBWR1THRATHRBMCHR1CRHR1 | |
| SCHEMBL28557800 | 0.83 | THRB (0.51) | THRATHRBCRHR1 | |
| SCHEMBL21749425 | 0.80 | NPBWR1 (0.37) | NPBWR1THRATHRBMCHR1CYP3A4 | |
| SCHEMBL21749428 | 0.80 | NPBWR1 (0.37) | NPBWR1THRATHRBMCHR1CYP3A4 | |
| SCHEMBL28566363 | 0.80 | PTGDR2 (0.42) | NPBWR1THRBPTGDR2 | |
| SCHEMBL21749429 | 0.80 | NPBWR1 (0.36) | NPBWR1THRATHRBPTGDR2 | |
| SCHEMBL21749370 | 0.80 | THRA (0.42) | NPBWR1THRATHRB | |
| SCHEMBL21749514 | 0.79 | NPBWR1 (0.42) | NPBWR1THRATHRBMCHR1CRHR1 | |
| SCHEMBL21749466 | 0.79 | NPBWR1 (0.38) | NPBWR1THRATHRBMCHR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805005-A | Thyroxine receptor beta agonist compounds | 拓臻股份有限公司 | 2021-05-14 | — | — | CN | disclosed |