Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 5/20 | 0.37 |
| ▸ | SGPL1 | O95470 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571851 | 1.00 | FAAH (0.41) | FAAHHSD17B3SIRT1OPRK1PNMT | |
| SCHEMBL28567951 | 1.00 | FAAH (0.41) | FAAHHSD17B3SIRT1OPRK1PNMT | |
| SCHEMBL27689519 | 0.89 | PNMT (0.40) | HSD17B3SIRT1PNMTADRA2AADRA2B | |
| SCHEMBL29113484 | 0.85 | BRD4 (0.39) | HSD17B3OPRK1SGPL1 | |
| SCHEMBL23306122 | 0.81 | SGPL1 (0.41) | FAAHHSD17B3PNMTSGPL1ADRA2A | |
| SCHEMBL13456262 | 0.81 | PLAU (0.47) | FAAH | |
| SCHEMBL2786999 | 0.78 | SIRT1 (0.52) | FAAHHSD17B3SIRT1OPRK1PNMT | |
| SCHEMBL23306121 | 0.77 | ITGB3 (0.39) | FAAHHSD17B3OPRK1PNMTSGPL1 | |
| SCHEMBL20262069 | 0.76 | HTR2A (0.41) | HSD17B3SRD5A1 | |
| SCHEMBL29187445 | 0.76 | SRD5A1 (0.41) | HSD17B3SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112867712-A | Carboxamides as ubiquitin-specific protease inhibitors | 瓦洛早期发现股份有限公司 | 2021-05-28 | — | — | CN | disclosed |