Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28866030 | 0.78 | VCAM1 (0.49) | IMPDH2ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28252836 | 0.78 | HTT (0.38) | IMPDH2STAT3ALDH1A1KMT2AMEN1 | |
| SCHEMBL2035587 | 0.74 | HTR6 (0.43) | ALDH1A1SMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL6297019 | 0.73 | IMPDH2 (0.45) | IMPDH2STAT3ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL28564220 | 0.71 | ALDH1A1 (0.54) | IMPDH2ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1778037 | 0.69 | IMPDH2 (1.00) | IMPDH2STAT3ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL30344324 | 0.69 | IMPDH2 (1.00) | IMPDH2STAT3ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6922436 | 0.69 | IMPDH2 (0.61) | IMPDH2STAT3ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3980032 | 0.69 | IMPDH2 (0.61) | IMPDH2STAT3ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27947289 | 0.69 | IMPDH2 (0.61) | IMPDH2STAT3ALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920170-B | N- (indol-5-yl) aromatic heterocyclic amide compound and preparation method and application thereof | 中国医科大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-112778316-B | N- (indole-5-yl) bicyclic aromatic amide compound and preparation method and application thereof | 中国医科大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-112920169-B | N-indolyl imidazole carboxamide compound and preparation method and application thereof | 中国医科大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-112920169-A | N-indolyl imidazole carboxamide compound and preparation method and application thereof | 中国医科大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-112920170-A | N- (indole-5-yl) aromatic heterocyclic amide compound and preparation method and application thereof | 中国医科大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-112778316-A | N- (indole-5-yl) bicyclic aromatic amide compound and preparation method and application thereof | 中国医科大学 | 2021-05-11 | — | — | CN | disclosed |