Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722883 | 0.75 | CCKBR (0.47) | SIRT5MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20722523 | 0.73 | KMT2A (0.50) | SIRT5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20722526 | 0.73 | KMT2A (0.50) | SIRT5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20722524 | 0.73 | KMT2A (0.50) | SIRT5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20722497 | 0.72 | KMT2A (0.49) | SIRT5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL21685914 | 0.72 | KMT2A (0.49) | SIRT5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL21685866 | 0.66 | SIRT5 (0.38) | SIRT5MEN1KMT2ATSHR | |
| SCHEMBL20722557 | 0.66 | SIRT5 (0.38) | SIRT5MEN1KMT2ATSHR | |
| SCHEMBL21685864 | 0.66 | SIRT5 (0.38) | SIRT5MEN1KMT2ATSHR | |
| SCHEMBL28645283 | 0.65 | GAA (0.39) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-A | Carboxamides as ubiquitin-specific protease inhibitors | 瓦洛早期发现股份有限公司 | 2021-05-28 | — | — | CN | disclosed |