Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30566318 | 1.00 | NAMPT (0.47) | NAMPTKDM4ELMNATHRBCYP19A1 | |
| SCHEMBL28574449 | 0.85 | NAMPT (0.46) | NAMPTKDM4ELMNATHRBCYP19A1 | |
| SCHEMBL28571346 | 0.82 | TBXAS1 (0.47) | LMNATBXAS1AGTR2HDAC1PADI4 | |
| SCHEMBL28569168 | 0.80 | HDAC8 (0.45) | KDM4ECYP19A1TBXAS1AGTR2PADI4 | |
| SCHEMBL30566323 | 0.80 | CYP19A1 (0.42) | CYP19A1TBXAS1AGTR2HDAC1PADI4 | |
| SCHEMBL28557217 | 0.80 | CYP19A1 (0.42) | CYP19A1TBXAS1AGTR2HDAC1PADI4 | |
| SCHEMBL28559267 | 0.80 | HDAC6 (0.47) | KDM4ELMNACYP19A1AGTR2HDAC1 | |
| SCHEMBL28572004 | 0.77 | TRPV1 (0.46) | KDM4ELMNATBXAS1HDAC1NPC1 | |
| SCHEMBL28433865 | 0.75 | ALDH1A1 (0.51) | LMNACYP19A1TBXAS1MEN1KMT2A | |
| SCHEMBL28433866 | 0.75 | ALDH1A1 (0.51) | LMNACYP19A1TBXAS1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142673-A | Arylalkenole derivative and preparation method and application thereof | 聊城大学 | 2020-12-29 | — | — | CN | claimed |
| CN-112142673-B | Aryl alkene azole derivative and preparation method and application thereof | 聊城大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-112142673-A | Arylalkenole derivative and preparation method and application thereof | 聊城大学 | 2020-12-29 | — | — | CN | disclosed |