Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4215555 | 0.98 | TSHR (0.50) | TSHRIDO1AGXTMAOBALDH1A1 | |
| SCHEMBL10875676 | 0.89 | TSHR (0.43) | TSHRIDO1AGXTMAOBALDH1A1 | |
| SCHEMBL666545 | 0.79 | TSHR (0.57) | TSHRIDO1AGXTMAOBALDH1A1 | |
| SCHEMBL1066575 | 0.78 | TSHR (0.50) | TSHRIDO1AGXTMAOBALDH1A1 | |
| SCHEMBL6873209 | 0.77 | TSHR (0.55) | TSHRIDO1AGXTMAOBALDH1A1 | |
| SCHEMBL20936609 | 0.76 | ALDH1A1 (0.44) | TSHRMAOBALDH1A1HIF1AL3MBTL1 | |
| SCHEMBL6258622 | 0.76 | TSHR (0.48) | TSHRIDO1AGXTMAOBALDH1A1 | |
| Benzene SCHEMBL25178056 | 0.75 | TSHR (0.52) | TSHRIDO1AGXTMAOBALDH1A1 | |
| SCHEMBL503 | 0.75 | TSHR (0.52) | TSHRIDO1AGXTMAOBALDH1A1 | |
| SCHEMBL2068701 | 0.75 | TSHR (0.52) | TSHRIDO1AGXTMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395587-B1 | PROCESS FOR THE PREPARATION OF IMIPENEM | RANBAXY LAB LTD (IN) | 2009-07-29 | — | — | EP | claimed |
| US-7462712-B2 | Process for the preparation of imipenem | RANBAXY LABORATORIES LIMITED (IN) | 2008-12-09 | — | — | US | claimed |
| US-20040220168-A1 | Process for the preparation of imipenem | RANBAXY LABORATORIES LIMITED (IN) | 2004-11-04 | — | — | US | claimed |
| EP-1395587-A4 | PROCESS FOR THE PREPARATION OF IMIPENEM | RANBAXY LAB LTD (IN) | 2004-09-15 | — | — | EP | claimed |
| EP-1395587-A1 | PROCESS FOR THE PREPARATION OF IMIPENEM | Ranbaxy Laboratories Limited (IN) | 2004-03-10 | — | — | EP | claimed |
| WO-2002094828-A1 | PROCESS FOR THE PREPARATION OF IMIPENEM | RANBAXY LABORATORIES LIMITED (IN) | 2002-11-28 | — | — | WO | claimed |
| US-20180066008-A1 | MACROLIDES WITH MODIFIED DESOSAMINE SUGARS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-03-08 | — | — | US | disclosed |
| EP-1847532-B1 | IGF-1R INHIBITOR | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-8293924-B2 | Process for the preparation of carbapenem antibiotic | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2012-10-23 | — | — | US | disclosed |
| US-8293924-B2 | Process for the preparation of carbapenem antibiotic | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2012-10-23 | — | — | US | disclosed |
| WO-2012081033-A2 | A PROCESS FOR PREPARATION OF IMIPENEM | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-06-21 | — | — | WO | disclosed |
| WO-2010146449-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF IMIPENAM | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2010-12-23 | — | — | WO | disclosed |
| US-20100311984-A1 | PROCESS FOR THE PREPARATION OF CARBAPENEM ANTIBIOTIC | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2010-12-09 | — | — | US | disclosed |
| EP-0250096-A1 | Isoxazolone derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| US-4698339-A | BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
| EP-0072014-B1 | COMBINATION OF 2-SUBSTITUTED PENEMS WITH DIPEPTIDASE INHIBITORS | MERCK & CO. INC. (US) | 1986-12-30 | — | — | EP | disclosed |
| EP-0137403-A2 | Carbapenems, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-17 | — | — | EP | disclosed |
| EP-0010573-B1 | NOVEL Z-2-ACYLAMINO-3-MONOSUBSTITUTED PROPENIC ACIDS AND THEIR ESTERS AND SALTS, AND PROCESSES FOR PREPARING THEM | MERCK & CO. INC. (US) | 1983-10-19 | — | — | EP | disclosed |
| EP-0010573-A1 | Novel Z-2-acylamino-3-monosubstituted propenic acids and their esters and salts, and processes for preparing them | MERCK & CO. INC. (US) | 1980-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180066008-A1 | MACROLIDES WITH MODIFIED DESOSAMINE SUGARS AND USES THEREOF | FUT6, MGAM, B3GNT2 | TSHR 3186/4885IDO1 724/4885AGXT 1129/4885 |
| US-20040220168-A1 | Process for the preparation of imipenem | ITPA, MGAM, SI | TSHR 4754/4885IDO1 1013/4885AGXT 778/4885 |
| US-20100311984-A1 | PROCESS FOR THE PREPARATION OF CARBAPENEM ANTIBIOTIC | MGAM, TREH, SI | TSHR 4577/4885IDO1 3881/4885AGXT 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.