Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K2 | P36507 | 3/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154022 | 0.88 | KDM4E (0.42) | KDM4ECNR1CNR2MEN1KMT2A | |
| SCHEMBL28564024 | 0.82 | KDM4E (0.50) | MAP2K2MAP2K1KDM4ECNR1CNR2 | |
| SCHEMBL3001658 | 0.81 | LMNA (0.52) | MAP2K2MAP2K1KDM4EMEN1KMT2A | |
| SCHEMBL29594757 | 0.78 | ALDH1A1 (0.53) | MAP2K2MAP2K1KDM4ECNR1CNR2 | |
| SCHEMBL28450562 | 0.78 | ALDH1A1 (0.53) | MAP2K2MAP2K1KDM4ECNR1CNR2 | |
| SCHEMBL3004233 | 0.75 | KDM4E (0.42) | KDM4ECNR1CNR2PTPN1DNMT1 | |
| SCHEMBL4158355 | 0.75 | KDM4E (0.44) | MAP2K2MAP2K1KDM4ECNR1CNR2 | |
| SCHEMBL4141571 | 0.75 | KDM4E (0.41) | MAP2K2MAP2K1KDM4ECNR1CNR2 | |
| SCHEMBL28914037 | 0.75 | MEN1 (0.60) | MAP2K2MAP2K1KDM4ECNR1CNR2 | |
| SCHEMBL2990529 | 0.74 | METTL3 (0.50) | MAP2K2MAP2K1KDM4ECNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942653-B | Erythromycin derivative and preparation method thereof | 北京理工大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-109942654-B | Macrolide and quinolone heterocomplex and preparation method thereof | 北京理工大学 | 2021-06-11 | — | — | CN | disclosed |