Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29194908 | 0.86 | PDE3B (0.44) | KDM4EHTTMETAP1ALDH1A1CA9 | |
| SCHEMBL4743605 | 0.82 | KDM4E (0.46) | KDM4EHTTMETAP1ALDH1A1CA9 | |
| SCHEMBL326339 | 0.74 | DRD2 (0.41) | METAP1CA9CA1CA2CA7 | |
| SCHEMBL1893435 | 0.74 | CA9 (0.50) | KDM4EHTTMETAP1ALDH1A1CA9 | |
| SCHEMBL3844075 | 0.73 | METAP1 (0.44) | KDM4EMETAP1ALDH1A1CA9CA2 | |
| SCHEMBL8938515 | 0.73 | ROCK1 (0.46) | — | |
| SCHEMBL30205899 | 0.73 | CA1 (0.36) | CA9CA1CA2CA7MAOB | |
| SCHEMBL28527525 | 0.73 | MAOA (0.42) | KDM4EALDH1A1CA9CA1CA2 | |
| SCHEMBL7076679 | 0.72 | MIF (0.34) | KDM4EHTTMETAP1ALDH1A1CYP19A1 | |
| SCHEMBL2523397 | 0.71 | PTPRC (0.57) | KDM4EMETAP1ALDH1A1CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924896-A | Synthesis method of naphthalenone compound | 北京蓝博特科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116874359-A | Synthesis method of naphthalenone compound | 北京蓝博特科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-108299169-B | Synthesis method of 6-chloro-3, 4-dihydro-2H-1-naphthalenone | 南京杰运医药科技有限公司 | 2021-04-30 | — | — | CN | disclosed |