Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2523397 | 0.89 | PTPRC (0.57) | CA9CA1CA2CA4CA7 | |
| SCHEMBL7038422 | 0.84 | CA2 (0.50) | CA9CA1CA2CA4CA7 | |
| SCHEMBL31439223 | 0.84 | CA2 (0.50) | CA9CA1CA2CA4CA7 | |
| SCHEMBL11352811 | 0.83 | CA1 (0.58) | CA9CA1CA2CA4CA7 | |
| SCHEMBL27374418 | 0.78 | LMNA (0.44) | CA9CA2MAPTPKMKDM4E | |
| SCHEMBL2529848 | 0.77 | PTPRC (0.55) | CA9CA1CA2CA4CA7 | |
| SCHEMBL12947560 | 0.76 | GSTP1 (0.56) | CA9CA1CA2CA4CA7 | |
| SCHEMBL28569831 | 0.74 | KDM4E (0.44) | CA9CA1CA2CA4CA7 | |
| SCHEMBL8884488 | 0.73 | CA2 (0.50) | CA9CA1CA2CA7MAPT | |
| SCHEMBL9586746 | 0.73 | CA9 (0.47) | CA9CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117623893-A | Preparation method of 5-hydroxy-1-indenone | 阜新清稷升科技有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-116924686-A | Glass powder for silver paste and preparation method thereof | 南通天盛新能源股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-119798018-A | Synthesis method of benzo cyclic ketone compound alpha-site dichloro substitution | 浙江大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-119707805-A | Preparation method of 6-hydroxyquinoline-4-carboxylic acid | 上海德浦生物医药科技有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-116535341-B | Method for synthesizing alpha-thiocyano-beta-dicarbonyl compounds by utilizing photocatalytic oxidation strategy | 新乡医学院 | 2025-01-28 | — | — | CN | disclosed |
| CN-114681454-B | Application of thiazole compound in preparation of novel coronavirus medicament for resisting SARS-COV-2 | 江南大学 | 2024-05-07 | — | — | CN | disclosed |
| CN-115819384-B | Method for preparing phthalic anhydride and derivatives thereof by catalyzing and oxidizing aromatic ketone by V-N-C material | 大连理工大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-117642375-A | Indenone and tetralone-ketone or hydroxyoxime as cancer therapeutic agents | 德克萨斯大学系统董事会 | 2024-03-01 | — | — | CN | disclosed |
| CN-117623893-A | Preparation method of 5-hydroxy-1-indenone | 阜新清稷升科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117623893-A | Preparation method of 5-hydroxy-1-indenone | 阜新清稷升科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-116924686-A | Glass powder for silver paste and preparation method thereof | 南通天盛新能源股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| US-8232311-B2 | Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators | ATHERSYS, INC. (US) | 2012-07-31 | — | — | US | disclosed |
| US-20110172283-A1 | Tricyclic Indeno-Pyrrole Derivatives as Serotonin Receptor Modulators | BENNANI YOUSSEF L | 2011-07-14 | — | — | US | disclosed |
| US-7935830-B2 | Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators | ATHERSYS, INC. (US) | 2011-05-03 | — | — | US | disclosed |
| US-20090239925-A1 | TRICYCLIC INDENO-PYRROLE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS | ATHERSYS, INC. | 2009-09-24 | — | — | US | disclosed |
| EP-1841738-A2 | TRICYCLIC INDENO-PYRROLE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS | Athersys, Inc. (US) | 2007-10-10 | — | — | EP | disclosed |
| WO-2007081299-A2 | TRICYCLIC INDENO-PYRROLE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS | ATHERSYS, INC. (US) | 2007-07-19 | — | — | WO | disclosed |
| US-20060025601-A1 | Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators | ATHERSYS, INC. | 2006-02-02 | — | — | US | disclosed |
| EP-0298466-A2 | Substituted alkene carboxylic acid amides and derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-11 | — | — | EP | disclosed |
| US-3985729-A | ANTIINFLAMMATORY AGENTS; CYCLIZATION OF 3-BENZYLAMINO-ALKYL-INDAN-1-OLS | SANDOZ, INC. (US) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172283-A1 | Tricyclic Indeno-Pyrrole Derivatives as Serotonin Receptor Modulators | HTR5A, HTR3E, HTR1E | CA9 4682/4885CA1 4852/4885CA2 4622/4885 |
| US-20060025601-A1 | Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators | HTR5A, HTR3E, HTR1E | CA9 4682/4885CA1 4852/4885CA2 4622/4885 |
| US-20090239925-A1 | TRICYCLIC INDENO-PYRROLE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS | HTR5A, HTR3E, HTR1E | CA9 4682/4885CA1 4852/4885CA2 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.