Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21335774 | 0.85 | GAA (0.36) | DRD2DRD3DRD1DRD5METAP1 | |
| SCHEMBL31463289 | 0.84 | GAA (0.50) | DRD2DRD3DRD1DRD5METAP1 | |
| SCHEMBL4133299 | 0.84 | GAA (0.50) | DRD2DRD3DRD1DRD5METAP1 | |
| SCHEMBL3844075 | 0.83 | METAP1 (0.44) | DRD2DRD3DRD1DRD5METAP1 | |
| SCHEMBL15540347 | 0.81 | MTNR1A (0.43) | CYP19A1CYP11B1 | |
| SCHEMBL30134456 | 0.81 | MPO (0.42) | DRD2DRD3DRD1DRD5METAP1 | |
| SCHEMBL1478437 | 0.81 | MPO (0.42) | DRD2DRD3DRD1DRD5METAP1 | |
| SCHEMBL4173550 | 0.80 | FYN (0.32) | — | |
| SCHEMBL30218170 | 0.79 | ALDH1A1 (0.40) | GAACA12CA9 | |
| SCHEMBL876228 | 0.78 | MMP2 (0.35) | CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208932-A1 | ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-06-27 | — | — | US | disclosed |
| US-11999819-B2 | Formulation containing a highly branched polymer, highly branched polymer and electro-optical device containing this highly branched polymer | MERCK PATENT GMBH (DE) | 2024-06-04 | — | — | US | disclosed |
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230159766-A1 | CONDUCTIVE POLYMER COMPOSITION, SUBSTRATE, AND METHOD FOR PRODUCING SUBSTRATE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-25 | — | — | US | disclosed |
| US-20230159456-A1 | N-SUBSTITUTED INDOLES | TERRAN BIOSCIENCES INC (US) | 2023-05-25 | — | — | US | disclosed |
| US-11427598-B2 | Spiro-cyclic amine derivatives as S1P modulators | AbbVie Deutschland GmbH & Co. KG (DE) | 2022-08-30 | — | — | US | disclosed |
| US-11427598-B2 | Spiro-cyclic amine derivatives as S1P modulators | AbbVie Deutschland GmbH & Co. KG (DE) | 2022-08-30 | — | — | US | disclosed |
| US-11208509-B2 | Polymer compound for conductive polymer and method for producing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-12-28 | — | — | US | disclosed |
| US-20210380738-A1 | CONDUCTIVE POLYMER COMPOSITION, SUBSTRATE, AND METHOD FOR PRODUCING SUBSTRATE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-12-09 | — | — | US | disclosed |
| US-20210277176-A1 | FORMULATION CONTAINING A HIGHLY BRANCHED POLYMER, HIGHLY BRANCHED POLYMER AND ELECTRO-OPTICAL DEVICE CONTAINING THIS HIGHLY BRANCHED POLYMER | MERCK PATENT GMBH (DE) | 2021-09-09 | — | — | US | disclosed |
| EP-0505972-B1 | Process for producing styrenic copolymer | IDEMITSU KOSAN CO (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5612462-A | Process for preparing bridged stereorigid metallocenes | WITCO GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5545785-A | Process for preparing biscyclopentadienyl compounds | WITCO GMBH (DE) | 1996-08-13 | — | — | US | disclosed |
| US-5543535-A | Organotin compounds useful in preparing bridged stereorigid metallocenes | WITCO GMBH (DE) | 1996-08-06 | — | — | US | disclosed |
| EP-0692486-A2 | Bisindenyl derivative and process for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| US-5217966-A | Synthetic drug molecules that mimic metalloenzymes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-06-08 | — | — | US | disclosed |
| US-5202317-A | SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0505972-A2 | Process for producing styrenic copolymer | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-09-30 | — | — | EP | disclosed |
| US-4985576-A | Bisindenyl derivative, and a process for the preparation thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0376154-A2 | Bisindenyl derivative and method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11427598-B2 | Spiro-cyclic amine derivatives as S1P modulators | S1PR1, S1PR3, S1PR2 | DRD2 505/4885DRD3 444/4885DRD1 872/4885 |
| US-20240208932-A1 | ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF | GPER1, ESR1, ESRRA | DRD2 674/4885DRD3 458/4885DRD1 583/4885 |
| US-20230159456-A1 | N-SUBSTITUTED INDOLES | TPH2, TPH1, AANAT | DRD2 185/4885DRD3 391/4885DRD1 538/4885 |
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | GAP43, SLC18A2, PNMT | DRD2 57/4885DRD3 98/4885DRD1 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.