SCHEMBL28570949

SCHEMBL28570949

O=CC1(c2ccccc2)OCCO1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MAPK1 P28482 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
HTR1A P08908 2/20 0.34
ADRA1D P25100 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 1/20 0.33
CYP2C9 P11712 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.33
GAA P10253 1/20 0.33
POLB P06746 1/20 0.33
AKR1C1 Q04828 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28411325 0.92 MAPK1 (0.36) TSHRL3MBTL1MAPK1SMN1; SMN2CHRM2
SCHEMBL684448 0.71 MEN1 (0.34) ALDH1A1MEN1CYP2C9KMT2AGAA
SCHEMBL6919085 0.71 TSHR (0.33) TSHRL3MBTL1MAPK1SMN1; SMN2CHRM2
SCHEMBL6482109 0.71 L3MBTL1 (0.44) TSHRL3MBTL1MAPK1SMN1; SMN2HTR1A
SCHEMBL29137626 0.70 SLC6A3 (0.38) MAPK1MEN1KMT2A
Water SCHEMBL11060484 0.70 MEN1 (0.33) ALDH1A1MEN1CYP2C9KMT2AGAA
Water SCHEMBL10535963 0.70 MEN1 (0.33) ALDH1A1MEN1CYP2C9KMT2AGAA
SCHEMBL14860790 0.69 TSHR (0.47) TSHRL3MBTL1MAPK1SMN1; SMN2CHRM2
SCHEMBL1256099 0.69 CHEK2 (0.39) TSHRL3MBTL1MAPK1SMN1; SMN2CHRM2
SCHEMBL17146580 0.69 CYP1A2 (0.38) TSHRL3MBTL1MAPK1SMN1; SMN2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109265328-B Method for green synthesis of benzoin diether driven by visible light 兰州大学 2021-06-04 CN disclosed