Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28570949 | 0.71 | TSHR (0.37) | TSHRMAPK1SMN1; SMN2L3MBTL1CHRM2 | |
| SCHEMBL8218672 | 0.68 | MAOB (0.36) | TSHRMAPK1SMN1; SMN2L3MBTL1CHRM2 | |
| SCHEMBL4952380 | 0.65 | LMNA (0.35) | TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL7772327 | 0.65 | LMNA (0.37) | TSHR | |
| SCHEMBL20115647 | 0.64 | L3MBTL1 (0.41) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9474097 | 0.64 | HTR1A (0.37) | — | |
| SCHEMBL28411325 | 0.64 | MAPK1 (0.36) | TSHRMAPK1SMN1; SMN2L3MBTL1CHRM2 | |
| SCHEMBL11515608 | 0.63 | CYP1A2 (0.36) | TSHRMAPK1SMN1; SMN2L3MBTL1CHRM2 | |
| SCHEMBL19417838 | 0.63 | CYP1A2 (0.36) | TSHRMAPK1SMN1; SMN2L3MBTL1CHRM2 | |
| SCHEMBL1256099 | 0.62 | CHEK2 (0.39) | TSHRMAPK1SMN1; SMN2L3MBTL1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737438-B2 | EFFECTIVE IN MULTIDRUG RESISTANT MICE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-05-18 | — | — | US | disclosed |