Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573260 | 0.80 | MAPT (0.63) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL17295043 | 0.76 | APLNR (0.69) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL4741225 | 0.74 | ALDH1A1 (0.57) | KMT2AMEN1MAPTGAAL3MBTL1 | |
| SCHEMBL3074293 | 0.74 | — | — | |
| SCHEMBL28176245 | 0.73 | L3MBTL1 (0.60) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL28600570 | 0.72 | L3MBTL1 (0.64) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL31388330 | 0.72 | L3MBTL1 (0.69) | KMT2AMEN1MAPTHTTL3MBTL1 | |
| SCHEMBL9454012 | 0.72 | L3MBTL1 (0.69) | KMT2AMEN1MAPTHTTL3MBTL1 | |
| SCHEMBL28569924 | 0.71 | PKM (0.55) | KMT2AMEN1HTTGAAL3MBTL1 | |
| SCHEMBL28575497 | 0.70 | L3MBTL1 (0.56) | KMT2AMEN1MAPTHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022178693-A1 | METHOD FOR PREPARING BENZOTHIAZOLE COMPOUND BY USING N-(2-BROMOPHENYL)THIOAMIDE UNDER PROMOTION OF VISIBLE LIGHT | 苏州大学 | 2022-09-01 | — | — | WO | disclosed |
| CN-112979581-B | Method for preparing benzothiazole compound from N- (2-bromophenyl) thioamide promoted by visible light | 苏州大学 | 2022-02-25 | — | — | CN | disclosed |
| CN-112979581-A | Method for preparing benzothiazole compound from N- (2-bromophenyl) thioamide promoted by visible light | 苏州大学 | 2021-06-18 | — | — | CN | disclosed |