Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR5 | O14804 | 1/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | PCNA | P12004 | 2/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024360 | 0.81 | ALDH1A1 (0.50) | TAAR5TAAR1MEN1KMT2AESR1 | |
| SCHEMBL2941282 | 0.81 | MEN1 (0.48) | TAAR5TAAR1MEN1KMT2AESR1 | |
| SCHEMBL359453 | 0.79 | TAAR1 (1.00) | TAAR5TAAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL29374539 | 0.79 | TAAR1 (1.00) | TAAR5TAAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10703684 | 0.79 | PDE7A (0.53) | TAAR5TAAR1MEN1KMT2AESR1 | |
| SCHEMBL13683235 | 0.79 | PDE10A (0.47) | TAAR5TAAR1MEN1KMT2AESR1 | |
| SCHEMBL6049180 | 0.78 | TAAR5 (0.42) | TAAR5TAAR1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL7020062 | 0.77 | ALDH1A1 (0.46) | TAAR5TAAR1MEN1KMT2AESR1 | |
| SCHEMBL20472303 | 0.77 | LTA4H (0.50) | TAAR5TAAR1MEN1KMT2AESR1 | |
| SCHEMBL13886676 | 0.77 | TAAR5 (0.79) | TAAR5TAAR1MEN1KMT2APCNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112822948-A | TAAR receptor agonists for the treatment of alopecia | 应用生物学公司 | 2021-05-18 | — | — | CN | claimed |
| CN-112822948-A | TAAR receptor agonists for the treatment of alopecia | 应用生物学公司 | 2021-05-18 | — | — | CN | disclosed |