Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573261 | 1.00 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL29832662 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL21820572 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL21820575 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL21808141 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL28569296 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL28904938 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AMAPTHCAR3 | |
| SCHEMBL28904936 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AMAPTHCAR3 | |
| SCHEMBL13991069 | 0.70 | LMNA (0.57) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL25347899 | 0.68 | LMNA (0.45) | ALDH1A1MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448908-A | Compounds for the treatment of specific leukemias | 拓臻股份有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-115215838-A | Compounds for the treatment of specific leukemias | 拓臻股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112770745-B | Compounds for the treatment of specific leukemias | 拓臻股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-112770745-A | Compounds for the treatment of specific leukemias | 拓臻股份有限公司 | 2021-05-07 | — | — | CN | disclosed |