Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31725471 | 0.85 | ELANE (0.51) | ELANEMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL12146965 | 0.78 | POLB (0.53) | ELANEMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28005933 | 0.78 | ELANE (0.50) | ELANEMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15792388 | 0.78 | ELANE (0.53) | ELANEMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28657306 | 0.74 | ELANE (0.49) | ELANEMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28915629 | 0.72 | ELANE (0.42) | ELANEMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28579341 | 0.71 | HTR3A (0.44) | ELANEBRD4HTR3AKCNH2L3MBTL1 | |
| SCHEMBL28695590 | 0.71 | HTR6 (0.51) | ELANEMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28914834 | 0.69 | ELANE (0.55) | ELANE | |
| SCHEMBL18188350 | 0.67 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4ESMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279849-A | N-difluoromethyl azaindole compound and synthesis method thereof | 丽水学院 | 2021-01-29 | — | — | CN | disclosed |