Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28643587 | 0.83 | L3MBTL1 (0.54) | ELANEMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28695590 | 0.82 | HTR6 (0.51) | ELANEMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28617149 | 0.80 | PKM (0.54) | ELANEMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL15792388 | 0.79 | ELANE (0.53) | ELANEMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31725471 | 0.77 | ELANE (0.51) | ELANEMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28005933 | 0.76 | ELANE (0.50) | ELANEMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12146965 | 0.76 | POLB (0.53) | ELANEMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4719367 | 0.74 | CCNB2 (0.44) | ELANEALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28573291 | 0.74 | ELANE (0.48) | ELANEMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4717733 | 0.69 | HTR6 (0.44) | ELANECCNB2CDK1CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444133-A | Isoxazole derivative containing glucose triazole structure and preparation method and application thereof | 绍兴文理学院元培学院 | 2021-09-28 | — | — | CN | claimed |
| CN-113444133-A | Isoxazole derivative containing glucose triazole structure and preparation method and application thereof | 绍兴文理学院元培学院 | 2021-09-28 | — | — | CN | disclosed |
| CN-113444133-A | Isoxazole derivative containing glucose triazole structure and preparation method and application thereof | 绍兴文理学院元培学院 | 2021-09-28 | — | — | CN | disclosed |