Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | GABRE | P78334 | 1/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731287 | 0.88 | GABRA1 (0.54) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28573345 | 0.85 | KMT2A (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6067942 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TDP1KMT2AMEN1RAB9A | |
| SCHEMBL5707256 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TDP1KMT2AMEN1RAB9A | |
| SCHEMBL31903 | 0.82 | HSD17B10 (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL5685046 | 0.81 | ALOX15 (0.61) | ALDH1A1TDP1KMT2AMEN1RAB9A | |
| SCHEMBL23861136 | 0.80 | ERN1 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL20249712 | 0.80 | HSD17B10 (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL27931484 | 0.78 | HSD17B10 (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29751827 | 0.78 | GPR35 (0.62) | ALDH1A1TDP1SMN1; SMN2HPGDS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110066278-B | Fused tricyclic compound and application thereof in medicines | 广东东阳光药业有限公司 | 2021-06-08 | — | — | CN | disclosed |