SCHEMBL28574669

SCHEMBL28574669

CC1=CC(C=O)Oc2cc(Br)ccc21

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.36
AHR P35869 3/20 0.33
S100A4 P26447 1/20 0.32
MAOB P27338 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28544024 0.81 CYP19A1 (0.43) MAOB
SCHEMBL27546376 0.76 MAOB (0.41) MAOB
SCHEMBL28043306 0.75 ALDH1A1 (0.40) MAOB
SCHEMBL29155456 0.73 RAB9A (0.43) MAOB
SCHEMBL29038350 0.69 AHR (0.34) PBRM1AHR
Ammonia Solution, Strong SCHEMBL5796209 0.63 MAOB (0.35) MAOB
SCHEMBL12458063 0.63 LMNA (0.44) PBRM1AHRMAOB
SCHEMBL28558061 0.63 SLC22A8 (0.33)
SCHEMBL9819102 0.62 PBRM1 (0.77) PBRM1MAOB
SCHEMBL28521090 0.61 MAPT (0.38) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112939950-A Carbonyl azetidine substituted coumarin fluorescent dye and synthetic method and application thereof 中国科学院大连化学物理研究所 2021-06-11 CN claimed
CN-112939950-A Carbonyl azetidine substituted coumarin fluorescent dye and synthetic method and application thereof 中国科学院大连化学物理研究所 2021-06-11 CN disclosed