Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.67 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13531595 | 0.86 | KMT2A (0.70) | ALDH1A1KMT2AENPP2NPC1RAB9A | |
| SCHEMBL2635694 | 0.85 | FKBP1A (0.66) | ALDH1A1KMT2AHTTMAPK1RECQL | |
| SCHEMBL9551409 | 0.83 | RAB9A (0.51) | ALDH1A1KMT2AHTTMAPK1RECQL | |
| SCHEMBL15919449 | 0.80 | FKBP1A (0.74) | ALDH1A1KMT2AHTTFKBP1APOLB | |
| SCHEMBL13534672 | 0.80 | FKBP1A (0.92) | ALDH1A1HTTFKBP1ARAB9APOLB | |
| SCHEMBL2712996 | 0.80 | FKBP1A (0.74) | ALDH1A1KMT2AHTTMAPK1RECQL | |
| SCHEMBL8320871 | 0.80 | ALDH1A1 (0.79) | ALDH1A1KMT2AHTTFKBP1APOLB | |
| SCHEMBL18425852 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KMT2AHTTMAPK1FKBP1A | |
| SCHEMBL4987745 | 0.79 | RECQL (0.67) | ALDH1A1KMT2ARECQLPOLBKDM4E | |
| SCHEMBL1115881 | 0.79 | CYP1A2 (0.64) | KMT2ANPC1RAB9APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759564-A | Diaryl urea compound and its preparation method and medicinal use | 中国医学科学院药物研究所 | 2021-05-07 | — | — | CN | disclosed |