Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575185 | 0.83 | ALDH1A1 (0.68) | RAB9ANPC1ALDH1A1KMT2AHTT | |
| SCHEMBL6286462 | 0.80 | CYP2C19 (0.53) | RAB9AALDH1A1KMT2AHTTTDP1 | |
| SCHEMBL1115881 | 0.79 | CYP1A2 (0.64) | RAB9ANPC1KMT2APOLBAKR1C3 | |
| SCHEMBL6021876 | 0.76 | KMT2A (0.43) | RAB9ANPC1ALDH1A1KMT2ATDP1 | |
| SCHEMBL27672213 | 0.76 | MAPT (0.48) | RAB9ANPC1ALDH1A1KMT2ATDP1 | |
| SCHEMBL5651256 | 0.75 | RAB9A (0.63) | RAB9ANPC1KMT2ASMN1; SMN2PHGDH | |
| SCHEMBL14139306 | 0.74 | MAPT (0.52) | RAB9AKMT2ATDP1POLBMAPT | |
| SCHEMBL17087197 | 0.74 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1KMT2AATM | |
| SCHEMBL4987745 | 0.73 | RECQL (0.67) | ALDH1A1KMT2ARECQLTDP1POLB | |
| SCHEMBL14378853 | 0.73 | GAA (0.61) | RAB9ANPC1ALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270302-A | Derivatives of tetrapeptides as CCK agonists | ABBOTT LABORATORIES (US) | 1993-12-14 | — | — | US | disclosed |
| WO-1991019733-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1991-12-26 | — | — | WO | disclosed |