Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560557 | 0.81 | TP53 (0.55) | MAPTKDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL7302756 | 0.77 | SMN1; SMN2 (0.43) | MAPTKDM4ELMNAALDH1A1TP53 | |
| SCHEMBL7302767 | 0.75 | SMN1; SMN2 (0.45) | MAPTKDM4ELMNAALDH1A1TP53 | |
| SCHEMBL11316497 | 0.69 | MAPT (0.48) | MAPTKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL13215131 | 0.64 | POLB (0.52) | MAPTKDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL8370314 | 0.64 | NPC1 (0.55) | MAPTALDH1A1TP53HTTKMT2A | |
| SCHEMBL28216207 | 0.64 | ACHE (0.56) | MAPTALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL27905951 | 0.63 | L3MBTL1 (0.43) | MAPTKDM4EALDH1A1L3MBTL1TP53 | |
| SCHEMBL13244175 | 0.63 | MAPT (0.53) | MAPTKDM4ELMNAALDH1A1CRHBP | |
| SCHEMBL20424921 | 0.63 | ALDH1A1 (0.51) | MAPTLMNAALDH1A1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349233-B | 3, 4-diphenyl-4H-1, 2, 4-triazole derivative and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-06-01 | — | — | CN | disclosed |