Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27475261 | 0.82 | PIN1 (0.68) | PIN1HSD17B10MAPK1USP2TSHR | |
| SCHEMBL7989950 | 0.82 | MAPK13 (0.51) | DGAT1PIN1HSD17B10TARBP2KDM4E | |
| SCHEMBL28582964 | 0.81 | TARBP2 (0.54) | PIN1HSD17B10MAPK1USP2TSHR | |
| SCHEMBL6520020 | 0.80 | PIN1 (0.52) | PIN1HSD17B10MAPK1USP2TSHR | |
| SCHEMBL21374324 | 0.80 | PIN1 (0.52) | PIN1HSD17B10MAPK1USP2TSHR | |
| SCHEMBL15592594 | 0.80 | HSD17B10 (0.56) | PIN1HSD17B10MAPK1USP2TSHR | |
| SCHEMBL31110150 | 0.78 | PIN1 (0.50) | DGAT1PIN1MAPK1HPGDERCC1 | |
| SCHEMBL17790243 | 0.78 | KDM4E (0.40) | HSD17B10KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL9049053 | 0.77 | KDM4E (0.50) | HSD17B10TSHRTARBP2KDM4EALDH1A1 | |
| SCHEMBL17803252 | 0.77 | KDM4E (0.58) | PIN1HSD17B10KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759551-B | 2, 5-substituent 1H-imidazole-4-carboxylate compound and synthetic purification method thereof | 宝鸡文理学院 | 2023-10-27 | — | — | CN | disclosed |
| CN-112759551-A | 2, 5-substituent 1H-imidazole-4-carboxylic ester compound and synthesis and purification method thereof | 宝鸡文理学院 | 2021-05-07 | — | — | CN | disclosed |