Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 7/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28582964 | 0.87 | TARBP2 (0.54) | PIN1HSD17B10KDM4ESMN1; SMN2TARBP2 | |
| SCHEMBL6520020 | 0.86 | PIN1 (0.52) | PIN1HSD17B10KDM4ESMN1; SMN2TP53 | |
| SCHEMBL21374324 | 0.86 | PIN1 (0.52) | PIN1HSD17B10KDM4ESMN1; SMN2TP53 | |
| SCHEMBL28297325 | 0.85 | KDM4E (0.60) | PIN1HSD17B10KDM4ESMN1; SMN2TP53 | |
| SCHEMBL11564100 | 0.84 | PIN1 (0.81) | PIN1HSD17B10MAPK1SLC9A1MAPT | |
| SCHEMBL15592594 | 0.82 | HSD17B10 (0.56) | PIN1HSD17B10KDM4ESMN1; SMN2TARBP2 | |
| SCHEMBL28575489 | 0.82 | DGAT1 (0.49) | PIN1HSD17B10KDM4ESMN1; SMN2TP53 | |
| SCHEMBL17803252 | 0.82 | KDM4E (0.58) | PIN1HSD17B10KDM4ESMN1; SMN2TP53 | |
| SCHEMBL4382123 | 0.81 | KDM4E (0.57) | PIN1HSD17B10KDM4ESMN1; SMN2TP53 | |
| SCHEMBL316552 | 0.81 | PIN1 (1.00) | PIN1KDM4EMAPK1SLC9A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177848-C | Bicyclic heteroaromatic compounds useful as LH agonists | ��˹��ŵ�� | 2004-12-01 | — | — | CN | disclosed |
| CN-1349535-A | Bicyclic heteroaromatic compounds useful as LH agonists | AKZO NOBEL NV (NL) | 2002-05-15 | — | — | CN | disclosed |