Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SPR | P35270 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423831 | 0.94 | ALDH1A1 (0.55) | CNR1TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL3390180 | 0.94 | ALDH1A1 (0.55) | CNR1TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL2854682 | 0.92 | ALDH1A1 (0.60) | HSD11B1PDE2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3390177 | 0.85 | KDM4E (0.49) | CNR1HSD11B1ALDH1A1KDM4ESPR | |
| SCHEMBL3423825 | 0.85 | KDM4E (0.49) | CNR1HSD11B1ALDH1A1KDM4ESPR | |
| SCHEMBL2856213 | 0.84 | CNR1 (0.47) | CNR1PDE2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10366974 | 0.82 | HSD11B1 (0.56) | CNR1HSD11B1ALDH1A1KDM4ESPR | |
| SCHEMBL2852200 | 0.82 | SPR (0.51) | CNR1PDE2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2851938 | 0.80 | SPR (0.56) | CNR1HSD11B1ALDH1A1KDM4ESPR | |
| SCHEMBL2857660 | 0.79 | LMNA (0.48) | CNR1TAS1R3TAS1R1TAS1R2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |