Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921295 | 0.74 | ALDH1A1 (0.54) | L3MBTL1LMNAGAANPC1RAB9A | |
| SCHEMBL29040744 | 0.73 | HCAR3 (0.40) | L3MBTL1HCAR3HSD17B10TP53GAA | |
| SCHEMBL3436674 | 0.71 | TP53 (0.63) | LMNATP53MAPT | |
| SCHEMBL23096137 | 0.71 | KDM4E (0.42) | LMNAHSD17B10TP53MAPTNPC1 | |
| SCHEMBL23269824 | 0.71 | HTR2B (0.56) | L3MBTL1HCAR3RAB9A | |
| SCHEMBL3436676 | 0.69 | TP53 (0.67) | LMNATP53MAPT | |
| SCHEMBL4258690 | 0.69 | HDAC6 (0.53) | L3MBTL1HCAR3HSD17B10HTTGAA | |
| SCHEMBL14382627 | 0.69 | L3MBTL1 (0.73) | L3MBTL1HCAR3HSD17B10MAPTHTT | |
| SCHEMBL3436678 | 0.69 | TP53 (0.70) | LMNATP53MAPT | |
| SCHEMBL3438305 | 0.68 | L3MBTL1 (0.57) | L3MBTL1HCAR3HSD17B10TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440534-B | Efficient synthesis of beta-chiral bicyclic or polycyclic imidazole derivatives | 南开大学 | 2021-05-28 | — | — | CN | disclosed |