Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29574248 | 0.85 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2HSD17B10FGFR1 | |
| SCHEMBL24265358 | 0.85 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2HSD17B10FGFR1 | |
| SCHEMBL28575730 | 0.73 | L3MBTL1 (0.50) | HCAR3NPC1MITFTP53NFKB1 | |
| SCHEMBL29040780 | 0.71 | TP53 (0.50) | NPC1TP53RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL30548190 | 0.71 | TP53 (0.50) | NPC1TP53RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL29574433 | 0.70 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL25423574 | 0.70 | HTR2B (0.50) | HCAR3L3MBTL1HSD17B10ACSS2GLP1R | |
| SCHEMBL30548180 | 0.69 | TP53 (0.54) | NPC1TP53RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL29491271 | 0.68 | LGALS8 (0.44) | HCAR3NPC1MITFTP53NFKB1 | |
| SCHEMBL29911008 | 0.68 | LGALS8 (0.44) | HCAR3NPC1MITFTP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507326-A | Compounds as GLP-1R agonists | 拓臻制药公司 | 2023-07-28 | — | — | CN | disclosed |