Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 6/20 | 0.58 |
| ▸ | RBP4 | P02753 | 1/20 | 0.45 |
| ▸ | MAP2 | P11137 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.44 |
| ▸ | WNT1 | P04628 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | CLK3 | P49761 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16252829 | 0.87 | MAP2K4 (0.52) | NTRK1RBP4MAPTMAP2K4MAPK1 | |
| SCHEMBL15253767 | 0.86 | RBP4 (0.46) | NTRK1RBP4DYRK1AWNT1AHR | |
| SCHEMBL956608 | 0.85 | PRKAG1 (0.55) | NTRK1RBP4DYRK1AWNT1AHR | |
| SCHEMBL591699 | 0.83 | RBP4 (0.45) | NTRK1RBP4DYRK1AWNT1AHR | |
| SCHEMBL23368472 | 0.83 | GSK3B (0.47) | NTRK1DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20207316 | 0.83 | NTRK1 (0.51) | NTRK1DYRK1AWNT1 | |
| SCHEMBL8877161 | 0.81 | JAK2 (0.54) | NTRK1DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL17039120 | 0.80 | JAK2 (0.64) | NTRK1DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL6195016 | 0.80 | DYRK1A (0.44) | NTRK1DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL15942818 | 0.80 | MAP2K4 (0.62) | NTRK1DYRK1AWNT1CLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438162-A | Modulators of MAS-related G protein receptor X4 and related products and methods | 伊赛恩特制药公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-112805282-A | Indazole-carboxamide derivatives and uses thereof | 广东东阳光药业有限公司 | 2021-05-14 | — | — | CN | disclosed |