SCHEMBL28577145

SCHEMBL28577145

CC(=O)N1CN(Cc2ccccc2)c2ccccc21.Nc1cccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 8/20 0.56
AMPD2 Q01433 7/20 0.45
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
KEAP1 Q14145 1/20 0.40
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
CNR2 P34972 1/20 0.38
BRS3 P32247 1/20 0.37
SIRT1 Q96EB6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28573688 0.99 BRD4 (0.55) BRD4AMPD2ALDH1A1HSD17B10CYP3A4
SCHEMBL28577143 0.74 KDM4E (0.48) BRD4ALDH1A1HSD17B10CYP3A4KDM4E
Acetic Acid SCHEMBL28299908 0.72 ALDH1A1 (0.71) ALDH1A1HSD17B10CYP3A4HPGDTSHR
Acetic Acid SCHEMBL27357071 0.72 ALDH1A1 (0.71) ALDH1A1HSD17B10CYP3A4HPGDTSHR
SCHEMBL4364295 0.70 BRD4 (0.55) BRD4AMPD2CYP3A4
Propionic Acid SCHEMBL30668813 0.68 ALDH1A1 (0.63) ALDH1A1HSD17B10CYP3A4HPGDTSHR
Carbamic Acid SCHEMBL6583530 0.67 ALDH1A1 (0.74) ALDH1A1HSD17B10CYP3A4HPGDTSHR
Oxalic Acid SCHEMBL4292229 0.67 ALDH1A1 (0.74) ALDH1A1HSD17B10CYP3A4HPGDTSHR
SCHEMBL1041747 0.67 BRD4 (0.51) BRD4LMNASIRT1
SCHEMBL29439121 0.67 BRD4 (0.51) BRD4LMNASIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113004206-B Naphthalene derivative fluorescent probe and preparation method and application thereof 齐齐哈尔大学 2022-06-17 CN disclosed
CN-113004206-A Naphthalene derivative fluorescent probe and preparation method and application thereof 齐齐哈尔大学 2021-06-22 CN disclosed