SCHEMBL28577189

SCHEMBL28577189

O=[N+]([O-])c1cccc(NN(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.56
MEN1 O00255 5/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
POLB P06746 3/20 0.53
MAPT P10636 3/20 0.53
DDX3X O00571 1/20 0.53
HTT P42858 1/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
ALDH1A1 P00352 4/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
KDM4E B2RXH2 2/20 0.50
GLA P06280 1/20 0.50
GAA P10253 1/20 0.50
LMNA P02545 1/20 0.50
TSHR P16473 1/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6373877 0.81 MEN1 (0.59) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL9847279 0.78 SMN1; SMN2 (0.58) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL2717131 0.78 HPGD (0.69) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL302395 0.77 MEN1 (0.49) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL225468 0.76 KMT2A (0.59) KMT2AMEN1NPC1RAB9APOLB
Water SCHEMBL9709472 0.76 MEN1 (0.48) KMT2AMEN1NPC1RAB9APOLB
Hydrazobenzene SCHEMBL27622421 0.75 LMNA (0.68) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL265235 0.75 CRHBP (0.55) KMT2AMEN1RAB9APOLBMAPT
SCHEMBL394734 0.75 KMT2A (0.67) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL238958 0.74 MEN1 (0.68) KMT2AMEN1NPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112274447-B Dendrobium officinale polysaccharide-hyaluronic acid soluble microneedle and preparation method thereof 杭州奥得科技有限公司 2023-03-10 CN disclosed
CN-113318018-A Rose extract and extraction method and application thereof 广东省禾基生物科技有限公司 2021-08-31 CN disclosed
CN-112274447-A Dendrobium officinale polysaccharide-hyaluronic acid soluble microneedle and preparation method thereof 杭州奥得科技有限公司 2021-01-29 CN disclosed