SCHEMBL28577336

SCHEMBL28577336

O=C=C1CCCC(C(=O)O)C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 2/20 0.35
TSHR P16473 2/20 0.35
SLC6A11 P48066 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLC6A13 Q9NSD5 1/20 0.35
PDK1 Q15118 1/20 0.33
POLB P06746 2/20 0.33
GAA P10253 1/20 0.33
GABRP O00591 3/20 0.32
GABRD O14764 3/20 0.32
GABRA1 P14867 3/20 0.32
GABRB1 P18505 3/20 0.32
GABRG2 P18507 3/20 0.32
GABRB3 P28472 3/20 0.32
GABRA5 P31644 3/20 0.32
GABRA3 P34903 3/20 0.32
GABRA2 P47869 3/20 0.32
GABRB2 P47870 3/20 0.32
GABRA4 P48169 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19466558 0.88 GABRP (0.38) TSHRLMNAPDK1POLBGAA
SCHEMBL20590460 0.78
SCHEMBL20590421 0.74 ALDH1A1 (0.43) SMN1; SMN2PDK1POLBGAAKDM4E
SCHEMBL21808904 0.74 CYP2C19 (0.33) TSHRPOLBGABRPGABRDGABRA1
SCHEMBL2422767 0.74 GABRP (0.41) SLC6A1TSHRSLC6A11LMNASMN1; SMN2
SCHEMBL15043867 0.72 THRB (0.42) SLC6A1TSHRSLC6A11LMNASMN1; SMN2
SCHEMBL3934728 0.72 THRB (0.42) SLC6A1TSHRSLC6A11LMNASMN1; SMN2
SCHEMBL535720 0.72 THRB (0.42) SLC6A1TSHRSLC6A11LMNASMN1; SMN2
SCHEMBL16731182 0.71 SLC6A1 (0.38) SLC6A1TSHRSLC6A11LMNASMN1; SMN2
SCHEMBL7712254 0.69 GAA (0.40) GAAGABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-213132809-U Movable low-temperature circulating pump for producing 3-carbonyl cyclohexanecarboxylic acid 泰州精英化成医药科技有限公司 2021-05-07 CN claimed
WO-2025103356-A1 SPIRO HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND INTERMEDIATE AND USE THEREOF 上海美悦生物科技发展有限公司 2025-05-22 WO disclosed
CN-120004907-A Spiro heterocyclic compounds, processes for their preparation, intermediates and uses 上海美悦生物科技发展有限公司 2025-05-16 CN disclosed
CN-213132809-U Movable low-temperature circulating pump for producing 3-carbonyl cyclohexanecarboxylic acid 泰州精英化成医药科技有限公司 2021-05-07 CN disclosed
CN-213132809-U Movable low-temperature circulating pump for producing 3-carbonyl cyclohexanecarboxylic acid 泰州精英化成医药科技有限公司 2021-05-07 CN disclosed
CN-213132809-U Movable low-temperature circulating pump for producing 3-carbonyl cyclohexanecarboxylic acid 泰州精英化成医药科技有限公司 2021-05-07 CN disclosed